Taurine surprised the scientists of H. Satoha's team... As a result of their research (Adv. Exp. Med. Biol.), they obtained evidence that taurine regulates the circulation of intracellular calcium in a manner corresponding to that of phosphocreatine.

Taurine participates in the process of “pumping out” calcium from the cellular cytoplasm, which is of great significance for the proper function of the cardiac muscle. However, its participation in the process has not been fully explained. As the energy in the form of ATP is absolutely essential in the “pumping out” of calcium, the role of phosphocreatine in the mechanism as an ATP provider seems clear. But how does taurine act here?

Some scientist ponder over another analogy occurring between taurine and phosphocreatine. Both the substances are cellular transporters of chemical groups: phosphocreatine – of phosphate groups, taurine – of sulphonic groups. Thanks to these properties, phosphocreatine builds an energy-rich nucleotide - ATP, whereas taurine builds PAPS.

ATP activates calcium “pumps”, binding phosphate groups to their protein components. Whereas PAPS, probably, binds sulphonic groups to their saccharic components.

Taurine also reacts directly with calcium itself so it regulates the intracellular concentration of this element in this manner as well, like phosphocreatine.

The studies seem to provide arguments for indications for the combined use of taurine and creatine as diet supplements, supporting the functions of the cardiovascular system.